Hexaquine Tablets Uses, Dosage, Side Effects, Precautions

Important to know about Hexaquine Tablets ?


This medicine is indicated for the treatment of nocturnal muscle cramps in adults.

Before prescribing Hexaquine Tablets, your doctor should evaluate the benefit to you of this treatment from the risk of developing side effects.

Hexaquine Tablets Uses, Dosage, Side Effects, Precautions

Hexaquine Tablets Tablets Uses, Dosage, Side Effects, Precautions

Hexaquine Tablets indication and Uses :

 Hexaquine Tablets Dosage :



1 to 3 tablets at bedtime, 174.4 mg to 261.6 mg quinine base daily.

Do not exceed 3 tablets maximum per day.

Patients should be monitored during the first few weeks of treatment because of side effects (see section 4.8 ). A benefit should be observed in the days following the start of treatment. In the absence of benefit after 4 weeks, treatment with quinine should be permanently discontinued.

Treatment with quinine is not a long-term treatment for idiopathic night cramps.

Administration mode:

Oral way.

Severe renal insufficiency

Dosage should be reduced in cases of severe renal impairment.

How it works Hexaquine Tablets :


Hexaquine Tablets Side Effects :

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Adverse effects not dependent on the dose ingested: allergic reactions sometimes serious, which can be manifested by:

· Skin reactions: redness, purpura, photosensitization,

· Decreased blood levels of platelets or all blood components,

· Some cases of liver damage (hepatitis) have been reported.

Adverse dose-dependent effects: ringing, hearing loss, dizziness, vision problems, headache.

If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

Hexaquine Tablets Interactions :

The data available to date do not suggest the existence of clinically significant interactions.

Hexaquine Tablets Warnings and Precautions :

Special warnings:

The occurrence of immuno-allergic accidents such as thrombocytopenia, hepatitis, allergy, requires the immediate and definitive cessation of this treatment and the subsequent eviction of quinine, including drinks containing it.

Quinine can lead to unpredictable and potentially life-threatening immunoallergic attacks. Quinine should not be used in patients who have had a history of side effects when administered as a drug or in drinks containing it.

Precautions for use:

Before using quinine for the treatment of idiopathic night cramps, all risks, ( see section 4.8 ) should be carefully considered in relation to the expected potential benefit. These risks are particularly present in the elderly.

Treatment with quinine should be considered only in the case of very painful and frequent cramps, when other causes of cramps have been ruled out and non-pharmacological measures have failed. Quinine should not be used for this indication during pregnancy.

The administration of quinine can lead to the appearance of cinchonism, generally more serious in case of overdose, but which can also appear for therapeutic doses usually used.

Patients should be warned not to exceed the prescribed doses because of the possibility of serious and irreversible side effects during overdose.

Any treatment of nocturnal idiopathic cramps with quinine should be discontinued if symptoms of cinchonism occur. These symptoms include dizziness, tinnitus, headache, nausea and blurred vision ( see sections 4.8 and 4.9 ).

This medicine contains azo coloring agents (orange-yellow (E110) and cochineal red A (E124)) and may cause allergic reactions.

This medicine contains sucrose. It is not recommended for use in patients with fructose intolerance, glucose-galactose malabsorption or sucrase / isomaltase deficiency.

Drive and use machines:

Not applicable.

Hexaquine Tablets Side Effects

Hexaquine Tablets Side Effects


Pregnancy :

During pregnancy, quinine should be reserved for the sole treatment of malaria.This medication should not be prescribed in pregnant women for the indication of idiopathic cramps.

A few cases of eye abnormalities and hearing impairment have been reported with high doses of quinine during pregnancy. At therapeutic doses, no incidents were reported.


It is advisable to avoid this medication during breastfeeding.

What happens if I overdose from Hexaquine Tablets ?

What is  Forms and Composition Hexaquine Tablets?


Coated tablet (dark orange):   Box of 18, blister packs of 9.

  p cp
Quinine benzoate 120 mg
(in anhydrous quinine: 87.2 mg / cp)
Thiamine (DCI) hydrochloride 32 mg

Excipients: purified natural essential oil of selected Melaleuca viridiflora , sucrose, corn starch, povidone, anhydrous colloidal silica (Aerosil 200), potato starch, hydrated colloidal silica (Sipernat 50), talc, stearic acid, purified water. Coating: gum arabic, hydrated colloidal silica (Levilite), shellac, rosin, gelatin, sucrose, talc, carnauba wax, yellow-orange S (E110), red cochineal A (E124), indigotin (E132).

Excipients with known effect: yellow orange (E110), red cochineal A (E124), sucrose.

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